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Infinx vs SamaCare

Two Prior Authorization vendors, side by side. Facts from public sources; judgments are ours.

At a glance

Derived from public facts · a rough scale, not a ranking

InfinxSamaCare
Pricing model

Enterprise contract (custom) · Software plus services, quote-based

Free to providers (funded by payers/pharma) · Pharma funds premium services and data

Speed to go live

Standard EHR integration project

Web portal, no IT project required

Automation model

Tech-enabled service · AI agents plus expert staff

Software platform · Unified PA portal, AI touchless tier

Built for

Mid-size groups, Enterprise systems, Billing companies

Small practices, Mid-size groups

Security posture

HITRUST, SOC 2 Type II, HIPAA

SOC 2 Type I, HIPAA

Company maturity

14 yrs (est. 2012)

8 yrs (est. 2018)

Financial backing

$186M reported · Growth (KKR minority stake 2024)

$33M+ · Series B

Named customers

None public

None public

Published results

No public numbers

No public numbers

Documented integrations

5 listed

4 listed

Third-party validation

None found

None found

Bottom line

  • Pick Infinx if you want prior auth and revenue cycle work handled by a blend of AI and human specialists rather than buying software your staff must run.
  • Pick SamaCare if you are a specialty practice buried in medical-benefit prior auths and want one free web portal replacing faxes and payer portals today.

Infinx

AI plus specialists for prior auth and patient access

Founded
2012
HQ
San Jose, CA
Stage
Growth (KKR minority stake 2024)
Raised
$186M reported

What it does

  • AI prior authorization determination, submission, and status tracking
  • Eligibility verification and benefits checks in one platform
  • Patient pay estimates before service
  • Certified specialists work exceptions automation cannot resolve
  • AR recovery and denial management services

Where it's strong

  • The AI-plus-human model delivers completed authorizations, not just software your staff still has to work.
  • Deep roots in high-volume prior auth specialties like radiology, labs, and cardiology.
  • Trusted by more than 900 provider organizations, with KKR and Norwest backing.

What buyers should weigh

  • Part of the value is outsourced labor, so compare its per-transaction economics against pure software options.
  • Named customer references are rare in public materials; case studies are anonymized.
  • Broad service catalog means implementation scope needs careful definition up front.

Integrations

EpicCernerathenahealtheClinicalWorksNextGen
Full Infinx profile →

SamaCare

Prior authorization platform for buy-and-bill specialty drugs

Founded
2018
HQ
San Francisco, CA
Stage
Series B
Raised
$33M+

What it does

  • One portal for all medical benefit PA submissions
  • AI-assisted form completion and payer requirements
  • Status tracking, renewals, and expiration alerts
  • Benefit verification and enrollment workflows
  • Approval analytics across a 20K-provider network

Where it's strong

  • Purpose-built for buy-and-bill drugs, a workflow retail-focused PA tools handle poorly.
  • Free for practices because pharma funds it, which removes the budget fight.
  • Network data from roughly 20,000 providers improves payer form accuracy and approval odds.

What buyers should weigh

  • The pharma-funded model means manufacturers see aggregate data; understand the data terms before signing.
  • Scope is medication PA for specialty drugs, not procedures, imaging, or surgical auths.
  • Smaller company (Series B) than incumbent networks, so vendor risk is higher than with McKesson or Optum.

Integrations

ModMedNextechOncoEMRPractice EHRs via interfaces
Full SamaCare profile →

Compare against the rest of Prior Authorization

Deciding between these two?

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